Serotonin

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Serotonin ( / ˌ s ɛr ə ˈ t oʊ n ᵻ n , ˌ s ɪər ə - / [6] [7] [8] ) or 5-hydroxytryptamine ( 5-HT ) is a monoamine neurotransmitter . Biochemically derived from tryptophan , [9] serotonin is primarily found in the gastrointestinal tract (GI tract), blood platelets , and the central nervous system (CNS) of animals, including humans. It is popularly thought to be a contributor to feelings of well-being and happiness . [10]

Serotonin is thought to be especially active in constricting smooth muscles, transmitting impulses between nerve cells, regulating cyclic body processes and contributing to wellbeing and happiness. 1

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Neuron. November 2013. Dissociable effects of dopamine and serotonin on reversal learning. Serotonin and dopamine are speculated to subserve motivationally opponent functions, but this hypothesis has not been directly tested. We studied the role of these neurotransmitters in probabilistic reversal learning in nearly 700 individuals as a function of two polymorphisms in the genes encoding the serotonin and dopamine transporters. Data provide direct evidence for doubly dissociable effects of serotonin and dopamine systems.

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